Evidence map›Paper›PMID 42757346›Full record

ArticleRSC advances2026

Design and evaluation of an amphiphilic biaryl ether library using a novel cell-based β-arrestin recruitment assay for the octopamine receptors of

Karoline Nordli, Jonne Laurila, Jørn H Hansen

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karoline NordliDepartment of Chemistry, UiT The Arctic University of Norway, Chemical Synthesis and Analysis Section N-9037 Tromsø Norway jorn.h.hansen@uit.no.
Jonne LaurilaInstitute of Biomedicine, Integrative Physiology & Pharmacology, University of Turku FIN-20520 Turku Finland jomila@utu.fi.
Jørn H HansenDepartment of Chemistry, UiT The Arctic University of Norway, Chemical Synthesis and Analysis Section N-9037 Tromsø Norway jorn.h.hansen@uit.no.ORCID https://orcid.org/0000-0002-3888-5217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 22-compound amphiphilic biaryl ether library inspired by the antifouling compound medetomidine has been designed and synthesized. The compound library was evaluated in a primary screening using a novel β-arrestin assay in CHO cells expressing the BiOctα-octopamine receptor of

Identifiers

PMID42757346
PMCPMC13585091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.