ArticlePatient preference and adherence2026
Knowledge, Attitudes, and Practices Regarding Oral Cancer Among Patients with Oral Cancer in Hunan Province, China: A Cross-Sectional Study.
Article in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to assess oral cancer-related knowledge, attitudes, and practices (KAP) among patients in Hunan Province, thereby providing a scientific basis for precise prevention, control, and effective intervention strategies against oral cancer. Methods: A cross-sectional survey was conducted in two tertiary hospitals in Hunan Province, China. A Chinese KAP questionnaire collected sociodemographic characteristics and assessed knowledge, attitudes, and practices. Results: A total of 326 patients were included; most were male (89.9%), married (88.7%), and rural residents (55.8%). Median scores were 7.0 (IQR 6.0-8.0) for knowledge, 53.0 (IQR 48.0-56.5) for attitude, and 31.0 (IQR 28.0-34.0) for practice; total KAP score was 91.0 (IQR 84.0-96.0). Structural equation modeling showed K→A (β=0.499, P=0.020) and A→P (β=0.571, P<0.001); the indirect effect of knowledge on practice via attitude was significant (β=0.285, P=0.024) with 83.6% mediation (P<0.001). In multivariable analysis, attitude predicted practice (B=0.425, P<0.001); absence of hypertension was associated with higher practice (B=1.348, P=0.023), whereas ≥2-generation family history of oral cancer was associated with lower practice (B=-4.510, P=0.008). KAP domains were positively correlated, strongest for attitude-practice (r=0.518, P<0.01). Conclusion: Participants demonstrated insufficient knowledge, positive attitudes, and suboptimal practices. Attitude fully mediated the knowledge-practice relationship, indicating that improving attitudes may be pivotal for behavior change. A feasible clinical implication is to implement structured, hospital-based education plus follow-up reinforcement, prioritizing patients with comorbid hypertension and those with strong family-history burden of oral cancer.
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