ReviewCureus2026
Cannabis Use and Risk of Periodontitis and Adverse Oral Health Outcomes: A Systematic Literature Review.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cannabis is widely consumed globally. Common methods of consumption include smoking, vaping, and consuming edibles. Despite its increasing use, the impact of cannabis consumption on the treatment and management of oral health disorders remains poorly understood. Cannabis has been associated with adverse oral effects such as periodontitis, xerostomia, caries, and gingivitis. These adverse oral effects complicate dental care. A systematic literature review was conducted, searching PubMed, EMBASE, and Cochrane databases from inception to May 31, 2024, to evaluate the effects of cannabis use on oral health, including its association with periodontitis and other adverse outcomes relevant to the treatment and management of oral health disorders among current or former adult users compared with never users. Eligible studies included randomized controlled trials (RCTs), quasi-RCTs, cohort studies, case-control studies, and cross-sectional surveys involving cannabis users and never users with diagnosed dental disorders; articles including synthetic cannabinoids were excluded; relevant articles were restricted to English-language studies on human subjects. The review protocol was registered with PROSPERO (CRD42024558418). Abstract and full-text reviews were conducted by two independent reviewers, with conflicts resolved by a third adjudicator. Crowe Critical Appraisal Tool (CCAT) Version 1.4 was used to assess the risk of bias within the included articles. The included studies were thematically analyzed and presented in descriptive tables. A total of 6,535 records were identified; after abstract and full-text review, 23 articles were included and underwent data extraction. The most prevalent condition was periodontitis, consisting of 11 studies, of which nine identified a negative relationship between cannabis use and periodontitis. Overall, cannabis use appears to be associated with an increased risk of adverse health outcomes like periodontitis, highlighting the need for patient screening. Other studies addressed health disorders such as cancer, dental caries, xerostomia, and altered anesthesia requirements. The interpretation of study results was limited by variability in study methodologies and reported outcomes. This work was supported by the Touro College of Pharmacy Student Summer Research Fellowship.
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Registered trials
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