Evidence map›Paper›PMID 42757177›Full record

ArticleChemical science2026

Liposomes can directly modulate serine hydrolase activity and lipid metabolism independent of cargo.

Payton E Lowrey, Olivia L Murtagh, Madeline Gunawardena, Rudra Pangeni, Qingguo Xu, Tobias O Jonson, Ku-Lung Hsu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Payton E LowreyDepartment of Chemistry, University of Texas at Austin 100 E 24th St, NHB 6.406, A5300 Austin TX 78712 USA ken.hsu@austin.utexas.edu +1 512-232-2146.
Olivia L MurtaghDepartment of Chemistry, University of Texas at Austin 100 E 24th St, NHB 6.406, A5300 Austin TX 78712 USA ken.hsu@austin.utexas.edu +1 512-232-2146.ORCID https://orcid.org/0009-0000-1352-4477
Madeline GunawardenaDepartment of Pharmaceutics, Virginia Commonwealth University Richmond VA 23298 USA.
Rudra PangeniDepartment of Pharmaceutical Sciences, Philadelphia College of Osteopathic Medicine Suwanee GA 30024 USA.
Qingguo XuDepartment of Pharmaceutics, Virginia Commonwealth University Richmond VA 23298 USA.ORCID https://orcid.org/0000-0003-3191-0771
Tobias O JonsonDepartment of Chemistry, University of Texas at Austin 100 E 24th St, NHB 6.406, A5300 Austin TX 78712 USA ken.hsu@austin.utexas.edu +1 512-232-2146.ORCID https://orcid.org/0009-0004-8028-8119
Ku-Lung HsuDepartment of Chemistry, University of Texas at Austin 100 E 24th St, NHB 6.406, A5300 Austin TX 78712 USA ken.hsu@austin.utexas.edu +1 512-232-2146.ORCID https://orcid.org/0000-0001-5620-3972

Funding

Endocannabinoid Biosynthesis in Inflammation and PainR01DA043571 · NIDA · UNIVERSITY OF VIRGINIA · PI Ku-Lung Hsu · 2017 to 2026
$3.5M
Chemical proteomic investigation of lipid kinase specificity and druggabilityR01AI169412 · NIAID · UNIVERSITY OF VIRGINIA · PI Ku-Lung Hsu · 2023 to 2026
$1.5M
NIAID NIH HHS R01 AI169412NIDA NIH HHS R01 DA043571
6 · The paper itself

Abstract

Liposomes are lipid-based nanoparticles that can be used to encapsulate and deliver small molecules, biologics, nucleic acids and other cargo for improved solubility, targeting and controlled release

Identifiers

PMID42757177
PMCPMC13584319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.