Evidence map›Paper›PMID 42757148›Full record

ArticleACS omega2026

Single-Frequency Microwave-Assisted Nanogel-Protein Complexation for Hybrid Biomaterial Fabrication.

Yunting Ma, Hikaru Takaya, Ryosuke Mizuta, Kazunari Akiyoshi, Yoshihiro Sasaki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunting MaDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Hikaru TakayaDepartment of Life & Health Sciences, Teikyo University of Science, 2-2-1 Senju-Sakuragi, Adachi-ku, Tokyo 120-0045, Japan.
Ryosuke MizutaDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Kazunari AkiyoshiDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Yoshihiro SasakiDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.ORCID https://orcid.org/0000-0003-1333-5347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of nanocarriers for protein delivery with adequate in vivo stability and precise control over protein release faces significant challenges. Microwave hyperthermia, which enables noninvasive and localized thermal regulation, is attracting increasing attention as an externally triggered drug delivery strategy. In the present study, we developed an efficient method for controlling the complexation of polysaccharide nanogels or their cross-linked hydrogels and proteins. Our strategy is to use highly controlled microwave irradiation with precisely regulated frequency and power. We found that programmable microwave power delivery with temperature feedback enabled rapid and reproducible thermal processing under the tested conditions. This offers a potential strategy for protein-biomaterial processing. The use of renewable polysaccharide-based nanogels, together with microwave-assisted process intensification, may provide a useful strategy for protein-biomaterial processing.

Identifiers

PMID42757148
PMCPMC13584551

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.