Maternal and neonatal outcomes in pregnant women with severe thrombocytopenia: insights from a retrospective 8-year cohort study in China.

Kangjia Chen, Qiao Liu, Jiawei Tang, Hui Chen, Xinghui Wen, Dunjin Chen, Shuguang Zhou, Fang He

Abstract read

In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kangjia ChenDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Qiao LiuDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Jiawei TangDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Hui ChenDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Xinghui WenDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Dunjin ChenDepartment of Obstetrics, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangzhou, Guangdong, China.

Shuguang ZhouDepartment of Gynecology and Obstetrics, Maternal and Child Medical Center of Anhui Medical University, Anhui Women and Children's Medical Center, The Fifth Affiliated Clinical College of Anhui Medical University, Hefei, Anhui, China.

Fang HeDepartment of Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe thrombocytopenia during pregnancy is uncommon but poses substantial challenges for obstetric management because of potential maternal bleeding and adverse neonatal outcomes. However, the relationship between the severity of maternal thrombocytopenia and maternal-neonatal outcomes remains unclear. Objectives: To characterize clinical features and maternal and neonatal outcomes across different platelet count strata in pregnant women with severe thrombocytopenia. Methods: We conducted a retrospective analysis of 175 cases over an 8-year period. Etiology, maternal characteristics, and maternal-neonatal outcomes were compared across 3 platelet count strata: ≤10, >10 to ≤20 × 10 Results: Primary immune thrombocytopenia was the predominant etiology (62.3%, 109/175). The incidence of postpartum hemorrhage was highest in the platelet count ≤ 10 × 10 Conclusion: Primary immune thrombocytopenia is the leading cause of severe thrombocytopenia during pregnancy. A lower platelet count, particularly ≤10 × 10

Indexed as

Pregnancy Complications, HematologicPurpura, Thrombocytopenic, IdiopathicThrombocytopeniaAdultChinaFemaleHumansIncidenceInfant, NewbornPlatelet CountPostpartum HemorrhagePregnancyPregnancy OutcomePremature BirthRetrospective StudiesRisk Factorsetiologyneonatal outcomepregnancypregnancy outcomesevere thrombocytopenia

Identifiers

PMID42757040

DOI10.1016/j.rpth.2026.106909

PMCPMC13584040

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.