ArticleBMJ public health2026
Occupational exposure to ionising radiation and central nervous system tumour mortality: a pooled analysis of Korean, French and US medical radiation workers.
Article in BMJ public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: High-dose ionising radiation (IR) is the only established modifiable risk factor for central nervous system (CNS) tumours, but the association with low- to moderate-dose IR is unclear. Methods: The BECOME ( Results: Cumulative brain dose averages were 10.5 (±13) mGy and 9.8 (±12.5) mGy for cases and controls, respectively. Overall, cumulative brain dose was not associated with CNS tumour death (OR=1.05; 95% CI 0.93 to 1.18 for a 10-mGy increase in cumulative brain dose) in all workers nor when the analysis was restricted to radiological technologists. A borderline significant dose-response association was found between occupational exposure to IR and CNS tumour death in medical workers first exposed after 1970 (OR=1.19; 95% CI 1.00 to 1.42 for a 10-mGy increase in cumulative brain dose). Conclusion: In this pooled nested case-control study, cumulative brain occupational radiation exposure was not associated with CNS mortality overall. More studies are needed of workers first exposed after 1970 and those conducting fluoroscopically guided interventional and nuclear medicine procedures.
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