Evidence map›Paper›PMID 42756872›Full record

ArticleACS omega2026

Electrochemical Synthesis of Building Blocks with a Structure Inspired by Nonsteroidal Anti-Inflammatory Drugs.

Jakub Adamek, Agnieszka Październiok-Holewa

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jakub AdamekSilesian University of Technology, Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, B. Krzywoustego 4, Gliwice 44-100, Poland.ORCID https://orcid.org/0000-0002-2960-6247
Agnieszka Październiok-HolewaSilesian University of Technology, Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, B. Krzywoustego 4, Gliwice 44-100, Poland.ORCID https://orcid.org/0000-0003-2643-6366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mild, metal- and additive-free, inexpensive electrochemical decarboxylation of arylalkanecarboxylic acids, including all the most important nonsteroidal anti-inflammatory drugs based on such a framework, is discussed. An efficient, nonaqueous, and essentially no-chromatography workup procedure enhances the attractiveness of the disclosed solution. This methodology can facilitate scaffold diversification by functionalization of NSAIDs or by providing easy access to building blocks from a simple arylalkanecarboxylic acid feedstock.

Identifiers

PMID42756872
PMCPMC13584791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.