ArticleObstetrics and gynecology international2026
Adenomyosis and Endometrial Carcinoma-Prognostic Significance of Coexistence. A Retrospective Analysis.
Article in Obstetrics and gynecology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Although frequently identified in hysterectomy specimens of women with endometrial carcinoma, the impact of adenomyosis on the prognosis of endometrial carcinoma remains uncertain. Therefore, we aimed to evaluate the prognostic significance of coexistent adenomyosis and endometrial carcinoma, focusing on histopathological features, staging, and recurrence rates. Methods: We conducted a retrospective analysis of 142 women treated during 2013-2023 for endometrial carcinoma, categorized as Type 1 or Type 2. Clinical, histopathological, and recurrence data were compared between those with and without adenomyosis. Results: Adenomyosis was identified in 32/142 women (22.5%). Among 119 with Type 1 endometrial carcinoma, 26 (21.8%) had adenomyosis. FIGO stage I-II disease was present in all of these and in 76/93 (81.7%) of those without adenomyosis ( Conclusion: We report an independent association of adenomyosis in Type 1 endometrial carcinoma with earlier-stage disease and reduced cervical stroma involvement. These findings highlight a potential association between adenomyosis and favorable tumor characteristics, warranting further studies to clarify the prognostic significance.
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