Evidence map›Paper›PMID 42756735›Full record

ArticleCJC open2026

Prognostic Impact of Main Pulmonary Artery Enlargement in Patients Undergoing Transcatheter Aortic Valve Replacement.

Dionysios Adamopoulos, Quentin Liabot, Léon Genecand, Christina Gkotsoulia, Sarah Mauler-Wittwer, Georgios Giannakopoulos, Jean-François Deux, Jakub Walenczak, Georgios Rovas, Marc Arcens and 5 more

Abstract read
In one paragraph

Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dionysios AdamopoulosFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Quentin LiabotFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Léon GenecandFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Christina GkotsouliaFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Sarah Mauler-WittwerFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Georgios GiannakopoulosFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Jean-François DeuxFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Jakub WalenczakDepartment of Diagnostics, Division of Radiology, Hôpitaux Universitaires de Genève (HUG), Geneva, Switzerland.
Georgios RovasLaboratory of Hemodynamics and Cardiovascular Technology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Marc ArcensFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Lindsey CroweDepartment of Internal Medicine, Division of Pneumology, Hôpitaux Universitaires de Genève (HUG), Geneva, Switzerland.
Hajo MüllerFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Nikolaos StergiopulosLaboratory of Hemodynamics and Cardiovascular Technology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Jean-Paul ValléeFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.
Stéphane NobleFaculty of Medicine, Department of Medicine, Geneva University, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary hypertension is characterized by extensive remodelling of the pulmonary tree, with enlargement of the pulmonary arteries. The predictive value of pulmonary hypertension in patients undergoing transcatheter aortic valve replacement (TAVR) has been demonstrated. We aimed to evaluate the prognostic impact of the pre-procedural main pulmonary artery (mPA) enlargement, assessed by computed tomography angiography, in patients undergoing TAVR for severe aortic stenosis (AS). Methods: We retrospectively analyzed 337 consecutive patients with AS from our local registry who underwent right heart catheterization and computed tomography angiography before TAVR. The cohort was divided into 2 groups according to the presence of an enlarged mPA (mPA axial diameter ≥ 29 mm for male patients and ≥ 27 mm for female patients, mPA Results: A significant correlation between invasive mean pulmonary artery pressure and mPA axial diameter was noted (Pearson Conclusions: Pre-procedural mPA enlargement is strongly associated with 1-year all-cause mortality in patients undergoing TAVR. This finding may pave the way for a more precise noninvasive risk stratification in patients with severe AS.

Indexed as

aortic valve stenosismain pulmonary artery enlargementpulmonary hypertensiontranscatheter aortic valve implantationtranscatheter aortic valve replacement

Identifiers

PMID42756735
PMCPMC13583577

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.