Evidence map›Paper›PMID 42756605›Full record

ArticleCureus2026

Poppers Maculopathy Due to Alkyl Nitrite-Infused Candle: A Case Report.

Tori Sayers, Murtaza K Adam

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tori SayersOphthalmology, The University of Texas Rio Grande Valley, Edinburg, USA.
Murtaza K AdamOphthalmology, Colorado Retina Associates, Lakewood, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recreational inhalation of alkyl nitrites ("poppers") is associated with a characteristic toxic maculopathy presumably due to ischemic changes in the central macula. Alkyl nitrite candles are available for purchase online and do not appear to be regulated. We report a unique retrospective case of vision loss following second-hand inhalation of vapor from a "poppers" candle in which a 29-year-old Hispanic male with no previous medical history presented with acute bilateral vision loss after attending a party at a nightclub. The patient denied sungazing, exposure to lasers, and a family history of inherited retinal disease. History was significant for use of a poppers-infused candle in a small, intimate private room. Visual acuity was 20/50 in both eyes. Central ellipsoid zone disruption was noted on bilateral optical coherence tomography. Visual acuity slowly improved to 20/40 in the right eye and 20/25 in the left eye over one year, with persistent ellipsoid zone disruption. In conclusion, alkyl nitrite-infused candles in confined spaces may be potent enough to cause poppers maculopathy.

Indexed as

alkyl nitritecandleinhalation retinopathymaculopathypoppers

Identifiers

PMID42756605
PMCPMC13583100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.