ArticleFrontiers in human neuroscience2026
Altered late semantic processing of food stimuli in female anorexia nervosa and atypical anorexia nervosa patients.
Article in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Anorexia Nervosa (AN) patients exhibit cognitive and neural disturbances during food processing, yet underlying mechanisms remain unclear. Our study investigated whether AN and Atypical AN (AAN) patients show altered neural, cognitive, and behavioral responses to high and low-calorie food stimuli, and whether these effects appear largely food-specific. Methods: Seventeen AN/AAN, 17 HCs, and 17 overweight/obese females viewed high and low-calorie food stimuli, rated palatability (yes/no), and completed an emotional picture viewing task (IAPS) while high-density EEG was recorded. Results: Palatability ratings did not differ significantly among groups; however, exploratory analyses suggested that patients with the restricting subtype (AN-R; Conclusion: AN/AAN individuals exhibit disrupted calorie-dependent semantic processing in right inferior temporal regions, indicating altered food evaluation. These findings provide a neural basis for restrictive eating in AN/AAN, highlighting the role of semantic processing in disorder-specific food disturbances.
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