Evidence map›Paper›PMID 42756001›Full record

ArticleFrontiers in pediatrics2026

Pediatric opioid and cannabis poisoning hospitalizations in the United States, 2016-2022: a national age-matched inpatient analysis.

Linor Fournier, Shereen Shehadeh, Mohamad Hamad Saied, David Maman, Giora Pillar

Abstract read
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Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Linor FournierDepartment of Pediatrics, Carmel Medical Center, Haifa, Israel.
Shereen ShehadehDepartment of Pediatrics, Carmel Medical Center, Haifa, Israel.
Mohamad Hamad SaiedDepartment of Pediatrics, Carmel Medical Center, Haifa, Israel.
David MamanThe Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Giora PillarDepartment of Pediatrics, Carmel Medical Center, Haifa, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Pediatric poisonings involving opioids and cannabis represent two evolving public health challenges. This study compared national inpatient outcomes, complications, and hospital charges among children and adolescents hospitalized with a principal diagnosis of opioid vs. cannabis poisoning in the United States. Methods: We conducted a retrospective cohort study using the Healthcare Cost and Utilization Project National Inpatient Sample from 2016 to 2022. Children and adolescents aged 0-18 years with a principal diagnosis of opioid or cannabis poisoning were identified using ICD-10-CM codes. National estimates were generated using the NIS discharge weight (DISCWT), with variance estimation accounting for NIS_STRATUM and HOSP_NIS. A 1:1 nearest-neighbor age-matched analysis was performed on the unweighted discharge records before application of the national weights. Survey-weighted logistic regression was used for binary outcomes, and survey-weighted linear regression was used for length of stay and total hospital charges. Multivariable models were adjusted for age, sex, race Results: The study included 17,555 weighted pediatric hospitalizations, comprising 10,780 opioid-related and 6,775 cannabis-related poisonings. The proportion classified as cannabis poisoning increased from 24.0% in 2016 to 47.2% in 2022 (survey-weighted trend odds ratio per year, 1.18; 95% CI, 1.14-1.23; Conclusion: Cannabis poisoning accounted for an increasing proportion of pediatric opioid and cannabis poisoning hospitalizations during the study period. Nevertheless, opioid poisoning was associated with greater respiratory morbidity, longer hospitalization, and higher hospital charges. These findings support opioid-related respiratory monitoring and harm-reduction efforts by clinicians and public health agencies, together with child-resistant packaging, safe-storage counseling, and caregiver education for cannabis products.

Indexed as

cannabis poisoninghealth care utilizationhospitalizationnational inpatient sampleopioid poisoningpediatric poisoningrespiratory failure

Identifiers

PMID42756001
PMCPMC13582458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.