ArticleFrontiers in surgery2026
When microsurgery is not an option: staged delayed reverse sural artery flap with ischaemic preconditioning for limb salvage in an elderly patient with chronic post-traumatic osteomyelitis-a case report.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Lower extremity reconstruction in elderly patients with post-traumatic osteomyelitis presents a formidable challenge. We report a 70-year-old female with hypertension, dyslipidaemia, and bilateral knee osteoarthritis who sustained a Gustilo-Anderson type IIIB open right ankle fracture with exposed calcaneus following a fall. The course was complicated by chronic osteomyelitis, managed with partial talectomy and total calcanectomy, antibiotic-impregnated cement spacer placement, cement exchange and prolonged culture-directed intravenous antibiotics. Following infection eradication, definitive hindfoot fusion using a structural femoral head allograft fixed with a retrograde tibiotalocalcaneal arthrodesis nail and compression screws was performed. However, a persistent soft-tissue defect with exposed bone precluded primary closure. Given her age, comorbidities and compromised local vascularity, free tissue transfer was deemed high-risk. Therefore, a 2-stage delayed reverse sural artery flap (RSAF) was selected. The first stage involved flap elevation with ischaemic preconditioning over 2 weeks via stepwise incremental incisional delay, followed by definitive transposition and inset. The donor site was managed with an ovine tendon collagen (OTC) matrix and split-thickness skin grafts (STSGs), supported by intermittent negative-pressure wound therapy (NPWT). At 6-months of follow-up, the flap remained viable and had fully survived, and the patient achieved partial weight-bearing ambulation. This case illustrates the decision-making framework for complex lower limb salvage, highlighting a staged reconstructive strategy integrating the delay phenomenon and adjunctive wound technologies to achieve durable limb salvage when microsurgical reconstruction is contraindicated.
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