ArticleFrontiers in plant science2026
The ADF4-RCAR12 module regulates ABA-mediated drought tolerance in
Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Drought is one of the most severe abiotic stresses limiting crop productivity, and abscisic acid (ABA)-induced stomatal closure is a key mechanism underlying plant drought resistance. Although ABA signaling has been extensively characterized in Methods: To investigate the role of Actin Depolymerizing Factor 4 (ADF4) in ABA signaling, we examined its interaction with RCAR12 using bimolecular fluorescence complementation (BiFC), GST pull-down, and co-immunoprecipitation (Co-IP) assays. Genetic interactions between ADF4 and RCAR12 were further analyzed using Results: ADF4 physically interacted with RCAR12 Discussion: These findings demonstrate that ADF4 functionally interacts with the ABA receptor RCAR12 and that the two proteins act synergistically in regulating ABA responses. Our results establish a link between actin dynamics and ABA receptor-mediated signaling and suggest that ADF4-RCAR12 coordination contributes to ABA-induced stomatal regulation and drought tolerance in Arabidopsis.
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