ArticleFrontiers in cardiovascular medicine2026
Evolution of electrocardiographic manifestations mimicking acute coronary syndrome secondary to hypoparathyroidism: a case report.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To promptly identify electrocardiographic (ECG) manifestations, including deep T-wave inversions and QT-interval prolongation, secondary to hypoparathyroidism and to improve its diagnostic accuracy and therapeutic management. Methods: We conducted a comprehensive analysis of the integrated treatment for a patient presenting with chest pain and evolving ECG changes secondary to hypoparathyroidism, supplemented by a review of the relevant literature. Results: In this case, a patient diagnosed with hypoparathyroidism presented with chest pain and dynamic ECG alterations. Following a confirmed diagnosis, treatment with calcium supplementation successfully alleviated the patient's chest pain and resulted in the complete normalization of the previously abnormal ECG findings. Conclusion: Clinical presentations mimicking angina pectoris, accompanied by secondary ECG changes such as deep T-wave inversions and QT-interval prolongation, are relatively uncommon in patients with hypoparathyroidism. A thorough evaluation combining clinical presentation, characteristic signs, and laboratory investigations can significantly reduce the rate of misdiagnosis.
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