ArticleFrontiers in endocrinology2026
Microbial metabolite-mediated modulation of enteroendocrine and immune pathways by
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: The gut microbiota-enteroendocrine axis contributes to the regulation of host energy homeostasis through microbial metabolites and satiety-related signaling. This study evaluated whether Methods: A dynamic multi-compartment colonic fermentation model was used to assess changes in cultivable microbial groups and short-chain fatty acid (SCFA) concentrations following probiotic treatment. Fermentation samples were subsequently evaluated in STC-1 enteroendocrine cells and a Caco-2/THP-1 co-culture model. In parallel, the metabolic and immunomodulatory effects of Results: Probiotic treatment selectively modulated cultivable microbial groups, increasing lactic acid bacteria and decreasing Discussion:
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