Evidence map›Paper›PMID 42755797›Full record

ArticleFrontiers in cardiovascular medicine2026

Combined assessment of carotid intima-media thickness and epicardial fat thickness for cardiovascular risk stratification in asymptomatic South Indian adults.

Ramesh Sankaran, Dolly Agarwal, Rahul Mittal, Shankar Srinivasan, Nagendra Boopathy Senguttuvan, Alex Karev, Sadhanandham Shanmugasundaram, Balasubramaniyan Jayanthi Venkata, Vinod Kumar Balakrishnan, Preetam Krishnamurthy and 2 more

Abstract read
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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors.

Ramesh SankaranCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Dolly AgarwalCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Rahul MittalDepartment of Health Informatics, Rutgers School of Health Professions, Rutgers Health, Rutgers University, Piscataway, NJ, United States.
Shankar SrinivasanDepartment of Health Informatics, Rutgers School of Health Professions, Rutgers Health, Rutgers University, Piscataway, NJ, United States.
Nagendra Boopathy SenguttuvanCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Alex KarevDivision of Cardiology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, United States.
Sadhanandham ShanmugasundaramCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Balasubramaniyan Jayanthi VenkataCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Vinod Kumar BalakrishnanCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Preetam KrishnamurthyCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Sadagopan ThanikachalamCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Murthy Jayanthi SatyanarayanaCardiac Care Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carotid intima-media thickness (cIMT) and epicardial fat thickness (EFT) are non-invasive imaging markers associated with cardiovascular risk. This study evaluated the associations between cIMT, EFT, individual cardiovascular risk factors, cumulative cardiovascular risk-factor burden in asymptomatic adults undergoing routine cardiovascular health assessment. Methods: A cross-sectional study was conducted in 925 asymptomatic adults aged ≥18 years undergoing routine cardiovascular health evaluations. Participants were classified into a control group without cardiovascular risk factors ( Results: Participants with one or more cardiovascular risk factors demonstrated significantly greater right cIMT (0.681 ± 0.186 mm vs. 0.576 ± 0.144 mm, Conclusions: Asymptomatic adults with cardiovascular risk factors demonstrated significantly greater carotid intima-media thickness and epicardial fat thickness than those without risk factors. Increasing age and cumulative cardiovascular risk-factor burden were associated with progressive increases in both imaging markers. These findings support the use of cIMT and EFT as complementary non-invasive imaging markers that may improve cardiovascular risk stratification alongside conventional risk assessment.

Indexed as

cardiovascular imagingcardiovascular risk factorscarotid intima-media thicknessepicardial fat thicknessSouth Asian populationvascular remodelling

Identifiers

PMID42755797
PMCPMC13581950

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