ArticleFrontiers in oncology2026
Case Report: Gastric glomus tumor with long-term dynamic multimodal imaging findings.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gastric glomus tumor (GGT) is a rare mesenchymal neoplasm with nonspecific clinical and imaging features, often leading to preoperative misdiagnosis. Its longitudinal imaging evolution remains poorly characterized. Herein, we report a 51-year-old man with a GGT in the gastric antrum who underwent 6-year multimodal imaging follow-up, including CT, MRI, and serial endoscopic ultrasonography (EUS). The lesion presented as a well-circumscribed subepithelial nodule with marked and persistent enhancement on CT. It showed slightly low signal intensity on T1-weighted imaging, slightly high signal intensity on T2-weighted imaging, and mild early arterial enhancement followed by persistent marked enhancement on dynamic contrast-enhanced MRI. Over the 6-year follow-up, the lesion showed an overall increase in size and a transition from a homogeneous to a heterogeneous hypoechoic appearance on serial EUS. It was initially misdiagnosed as a gastrointestinal stromal tumor. Histopathology confirmed the diagnosis of GGT. This case highlights that GGT may exhibit characteristic yet dynamic imaging features on long-term follow-up. Recognition of these features across modalities may improve preoperative diagnostic accuracy.
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