ArticleFrontiers in pharmacology2026
Quantitative characterization of L-citrulline as a precursor of L-arginine in rats: pharmacokinetic basis for nitric oxide-mediated effects.
Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
L-Arginine (ARG) is the primary substrate for nitric oxide (NO) synthesis via nitric oxide synthase (NOS), and L-citrulline (CIT) is its endogenous precursor. Although oral CIT has been reported to increase systemic ARG levels, the quantitative basis for its
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