Evidence map›Paper›PMID 42755620›Full record

ArticleFrontiers in medicine2026

Direct visualization-guided endoscopic management of complex colonic diverticular disease: a proof-of-concept case series.

Tianjie Han, Junshan Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tianjie HanDepartments of Hematology, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China.
Junshan LiDepartment of Gastroenterology, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Complex colonic diverticular disease, including diverticular bleeding, inflammatory diverticular disease, presents substantial therapeutic challenges for conventional colonoscopy because of limited intradiverticular visualization, difficult access, and restricted maneuverability. Failure to precisely localize the culprit lesion or inflammatory nidus may lead to recurrent symptoms, delayed treatment, or surgical intervention. The EyeMax direct visualization system, originally designed for pancreatobiliary interventions, may provide a novel strategy for targeted intradiverticular diagnosis and therapy. Aim: To evaluate the feasibility, safety, and potential clinical applications of the EyeMax direct visualization system in the endoscopic management of complex colonic diverticular disease. Methods: We conducted a retrospective proof-of-concept case series of patients with complex colonic diverticular disease who underwent EyeMax-assisted endoscopic intervention at a tertiary hospital between January 2024 and July 2026. Included patients had diverticular bleeding, diverticulitis with localized inflammation or purulent cavity, or diverticular fecalith incarceration. Primary outcome was technical success, defined as successful intradiverticular access and completion of intended intervention under direct visualization. Secondary outcomes included clinical success, adverse events, recurrence, and need for surgery. Results: Seven patients were included, comprising diverticular bleeding ( Conclusion: In this preliminary assessment, the EyeMax system demonstrates feasibility for managing complex colonic diverticular disease, with potential utility in diverticular bleeding, diverticulitis, and fecalith incarceration. These findings are preliminary, and the concept of direct visualization-guided precision endoscopy warrants validation in larger prospective multicenter studies.

Indexed as

colonic diverticular diseasedirect visualizationdiverticular bleedingendoscopyEyeMax systeminflammatory diverticular disease

Identifiers

PMID42755620
PMCPMC13581646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.