SynthesisFrontiers in neurology2026
Cognitive impairment in vestibular migraine: a PubMed-based systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Vestibular migraine (VM) is a leading cause of recurrent vertigo, and many patients describe cognitive symptoms such as "brain fog," slowed thinking, and forgetfulness; however, the magnitude and consistency of objectively measured cognitive impairment in VM have not been clearly quantified. We therefore conducted a PubMed-only systematic review (2010-2025; English; humans) of observational studies reporting quantitative behavioral cognitive outcomes or explicit impairment thresholds in adults with VM. Two reviewers independently extracted data and assessed the risk of bias using ROBINS-I. Continuous outcomes were pooled as standardized mean differences (SMD; Hedges g; random-effects REML), while the prevalence of study-defined cognitive impairment in VM cohorts was synthesized using the Freeman-Tukey transformation; when required, medians and measures of dispersion were converted to means and standard deviations. Results: Six studies met the inclusion criteria, of which four contributed to the primary meta-analysis (VM Conclusion: Based on this focused, single-database rapid review, current evidence suggests adults with VM may exhibit moderate-to-large decrements in global cognition and executive control, supporting the consideration of cognitive screening and multidisciplinary management in routine VM care. Future work should prioritize standardized cognitive outcomes and mechanistic studies to clarify causal pathways and improve clinical translation. Systematic review registration: https://inplasy.com/projects/, Identifier, INPLASY2025100115.
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