Evidence map›Paper›PMID 42755539›Full record

ReviewFrontiers in cellular neuroscience2026

The effects of abused drugs on ferroptosis pathways: potential therapeutic targets for substance use disorders.

Tamara Bouchard, Brooke Russell, Liam Liyang Guo, Tina Nguyen, Yan Cheng, Yan Y Sanders, Ming-Lei Guo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamara BouchardDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.
Brooke RussellDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.
Liam Liyang GuoKeck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Tina NguyenDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.
Yan ChengDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.
Yan Y SandersDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.
Ming-Lei GuoDepartment of Biological and Translational Department, Macon and Joan Brock Eastern Virginia Medical School/Virginia Health Sciences, Old Dominion University, Norfolk, VA, United States.

Funding

Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and CocaineR01DA054826 · NIDA · OLD DOMINION UNIVERSITY · PI GUO, MINGLEI, KIM, WOONG-KI · 2021 to 2025
$2.3M
Effects of social isolation and loneliness during early life on neurocognitive development and addictionR34DA061156 · NIDA · OLD DOMINION UNIVERSITY · PI BRITTEN, RICHARD ANTONY, GUO, MINGLEI · 2024 to 2025
$720k
Mg-based therapy for mitigating HAND and neuropsychiatric symptoms in the condition of chronic HIV infectionR21AG090171 · NIA · OLD DOMINION UNIVERSITY · PI GUO, MINGLEI · 2024 to 2024
$440k
NIA NIH HHS R21 AG090171NIDA NIH HHS R01 DA054826NIDA NIH HHS R34 DA061156
6 · The paper itself

Abstract

Substance use disorders (

Indexed as

ferroptosisneurodegenerationneuroinflammationROSsubstance use disorder

Identifiers

PMID42755539
PMCPMC13581560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.