Evidence map›Paper›PMID 42755532›Full record

ArticleFrontiers in nutrition2026

Beyond donor eligibility: nutritional and lifestyle heterogeneity and implications for long-term donor health preservation.

Elisa Mazza, Samantha Maurotti, Yvelise Ferro, Francesca Rita Noto, Carmelo Pujia, Nancy Paone, Alessia Sestito, Marta Moraca, Ilda Fatima Martino, Arturo Pujia and 1 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisa MazzaDepartment of Clinical and Experimental Medicine, University Magna Græcia, Catanzaro, Italy.
Samantha MaurottiDepartment of Clinical and Experimental Medicine, University Magna Græcia, Catanzaro, Italy.
Yvelise FerroDepartment of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.
Francesca Rita NotoDepartment of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.
Carmelo PujiaClinical Nutrition Unit, AOU "Renato Dulbecco", Catanzaro, Italy.
Nancy PaoneDepartment of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.
Alessia SestitoClinical Nutrition Unit, AOU "Renato Dulbecco", Catanzaro, Italy.
Marta MoracaClinical Nutrition Unit, AOU "Renato Dulbecco", Catanzaro, Italy.
Ilda Fatima MartinoDepartment of Clinical and Experimental Medicine, University Magna Græcia, Catanzaro, Italy.
Arturo PujiaDepartment of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.
Tiziana MontalciniDepartment of Clinical and Experimental Medicine, University Magna Græcia, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Blood donor eligibility is essential for donation safety, but it may not fully capture nutritional, metabolic, and lifestyle-related vulnerabilities that can affect donor health over time. As transfusion systems increasingly rely on regular donors, identifying modifiable factors that may support long-term donor health and retention is becoming increasingly relevant. This study aimed to characterize nutritional and lifestyle heterogeneity, peri-donation dietary behaviors, and donation-related outcomes in adult blood donors. Methods: This cross-sectional survey used a structured online questionnaire assessing anthropometric characteristics, lifestyle factors, habitual dietary intake, nutrition-related awareness, peri-donation dietary behaviors, self-reported history of iron deficiency, and post-donation symptoms. Dietary profiles were identified using principal component analysis followed by k-means clustering. Multivariable logistic regression models were used to explore factors associated with iron deficiency history and post-donation symptoms. Results: The study included 698 adult blood donors. Overweight and obesity affected nearly half of the cohort and were more frequent among men and older donors, whereas women more frequently reported iron deficiency history and post-donation symptoms. Three dietary profiles were identified: Western/ultra-processed, Mediterranean-like, and mixed beverage-oriented. Younger donors were more frequently represented in less favorable dietary and lifestyle profiles, whereas older donors showed more favorable dietary habits despite a higher prevalence of overweight/obesity. In multivariable analyses, female sex was independently associated with iron deficiency history (OR 4.62, 95% CI 3.20-6.68; Discussion: These findings suggest that adult blood donors represent a nutritionally and metabolically heterogeneous population despite donation eligibility. These findings support the potential relevance of structured nutritional counseling, lifestyle-oriented prevention, and recovery-focused recommendations within donor care pathways, although their impact on long-term donor health, continued eligibility, and donor retention should be evaluated in future prospective and interventional studies.

Indexed as

BMIdietary patternsdonationlifestylenutrition

Identifiers

PMID42755532
PMCPMC13581511

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.