Evidence map›Paper›PMID 42755531›Full record

ArticleFrontiers in neurology2026

The predictive value of the leuko-glycemic index in spontaneous intracerebral hemorrhage patients undergoing neurosurgical operation: a retrospective cohort study.

Jian Sun, Yunhan Zhan, Aiwen Zhang, Mingchao Fan

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Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jian SunDepartment of Neurosurgical Intensive Care Unit, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yunhan ZhanDepartment of Neurosurgical Intensive Care Unit, The Affiliated Hospital of Qingdao University, Qingdao, China.
Aiwen ZhangDepartment of Central Sterile Supply, The Affiliated Hospital of Qingdao University, Qingdao, China.
Mingchao FanDepartment of Neurosurgical Intensive Care Unit, The Affiliated Hospital of Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This research sought to determine the prognostic utility of the leuko-glycemic index (LGI) in predicting surgical outcomes following spontaneous intracerebral hemorrhage (ICH), and to establish its potential role in clinical outcome assessment. Methods: A retrospective cohort study was performed using medical records of spontaneous ICH patients who received surgical intervention at Qingdao University Affiliated Hospital between January 2013 and December 2023. Patients were stratified into two cohorts according to their 90-day modified Rankin Scale (mRS) scores. Associations between inflammatory biomarkers and postoperative prognosis were examined, and a predictive framework was constructed. The discriminatory power and optimal threshold of LGI were determined via receiver operating characteristic (ROC) analysis. Results: Of the 720 enrolled postoperative ICH patients, 224 (31.11%) achieved a favorable prognosis, while 496 (68.89%) had an unfavorable outcome. Univariate analysis revealed statistically significant disparities in several variables: age, presence of intraventricular hemorrhage, GCS score at admission, timing of surgical intervention, LGI, serum potassium, blood glucose, and heart rate. Binary logistic regression identified LGI (OR, 1.009; 95% CI, 1.004-1.013; Conclusion: Both preoperative LGI and admission GCS score serve as reliable indicators of clinical prognosis in spontaneous ICH patients undergoing neurosurgical operation.

Indexed as

Blood GlucoseCerebral HemorrhageGlycemic IndexNeurosurgical ProceduresAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesBlood GlucoseGlasgow coma scaleleuko-glycemic indexmodified Rankin scaleprognosisspontaneous intracerebral hemorrhage

Identifiers

PMID42755531
PMCPMC13581521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.