Evidence map›Paper›PMID 42755507›Full record

ArticleFrontiers in physiology2026

Xi Zheng, Hongbin Lu, Meiyang Chen, Ying Xu, Chensheng Lin, Yi Lv, Yanding Zhang, Xuefeng Hu, Minkui Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xi ZhengFujian Key Laboratory of Oral Diseases & Clinical Research Center for Oral Tissue Deficiency Diseases of Fujian Province & Fujian Provincial Engineering Research Center of Oral Biomaterial, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Hongbin LuFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Meiyang ChenFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Ying XuFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Chensheng LinFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Yi LvFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Yanding ZhangFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Xuefeng HuFujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Minkui LinFujian Key Laboratory of Oral Diseases & Clinical Research Center for Oral Tissue Deficiency Diseases of Fujian Province & Fujian Provincial Engineering Research Center of Oral Biomaterial, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mutations in Methods: We investigated the function of Results: Mutant embryos exhibited complete agenesis of maxillary incisors and impaired development of mandibular incisors. Although tooth initiation was preserved, mutant maxillary incisors failed to progress through the bud-to-cap transition and lacked a discernible enamel knot. Transcriptomic profiling of E13.5 dental mesenchyme revealed alterations in odontogenic gene programs, including genes associated with BMP and Wnt signaling pathways. Consistent with these findings, expression of Discussion: These findings identify

Indexed as

Alx1BMP signalingenamel knotfrontonasal dysplasiaincisor morphogenesisneural crest-derived mesenchymeWnt signaling

Identifiers

PMID42755507
PMCPMC13581496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.