SynthesisFrontiers in neurology2026
Treatment first, transport second: rethinking stroke management with mobile stroke units-A systematic review and meta-analysis of controlled trials.
Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Stroke is a significant cause of morbidity and mortality, with profound medical and economic consequences. Accurate diagnosis and minimizing delays in acute stroke management has become a global priority. Mobile stroke units (MSUs) have the potential to effectively shorten key time intervals. Objective: We conducted this review aiming to investigate the benefits of MSU implementation on functional, safety and time metrics outcomes in acute stroke care. Moreover, we assessed whether the presence of an onboard neurologist is essential for MSU implementation. Results: The analysis consisted of 10 studies involving 13,110 patients (4,350 MSU; 8,760 EMS). The pooled median difference favors MSU intervention over the control by 26.3 min [95% CI (20.1-32.4), Conclusions: In this review, it was demonstrated that MSUs have markedly improved some of the critical time metrics of acute stroke care through clinically meaningful reductions of ~10-35 min, while maintaining safety outcomes comparable to traditional EMS care. We found no significant differences considering the impact of onboard and remote neurologist models in MSUs, highlighting that remote neurologists in MSUs could potentially be a more cost-effective model. Systematic review registration: PROSPERO; registration number: CRD420261297860.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.