SynthesisF1000Research2026
Night Shift Work and Vascular Function Parameters: A Systematic Review of Occupational and Healthcare Evidence with Implications for Radiographers.
Synthesis in F1000Research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Shift workers face elevated cardiovascular disease risk. Radiographers represent a unique occupational group exposed to both low-level ionizing radiation and chronic night shift work - each independently associated with subclinical vascular disease - yet no synthesis exists on vascular function in this population. Objective: To systematically identify and narratively synthesize evidence on associations between night shift work and objective vascular parameters - including CIMT, PWV, augmentation index, reactive hyperaemia index, and cerebrovascular white matter integrity - and assess applicability to radiographers. Methods: A systematic search of Medline, Embase, Web of Science, Scopus, and CINAHL was conducted per PRISMA 2020. Eligible studies were primary observational studies reporting objective vascular outcomes in night shift workers. Risk of bias was assessed using JBI critical appraisal tools. Narrative synthesis with vote-counting was used; meta-analysis was not feasible due to heterogeneity. Results: Ten studies from 2,257 records met the inclusion criteria across five vascular outcome domains. Cumulative night shift exposure was associated with increased arterial stiffness (PWV +1.29 m/s over 3 years) and reduced endothelial function (RHI -0.054). Associations were frequently attenuated to non-significance after covariate adjustment, and CIMT findings were directionally inconsistent. Poor sleep quality independently predicted higher CIMT in healthcare workers. Former shift workers showed persistent cerebrovascular white matter changes. Conclusion: Current evidence suggests possible associations between night shift work and arterial stiffness, though findings for other vascular outcomes remain inconsistent. No primary data exist for radiographers. The hypothesis of synergistic vascular injury from combined radiation and circadian disruption is biologically plausible but requires direct investigation through longitudinal, occupation-specific studies with standardized vascular outcome measures. Study Registration: The review was developed and recorded following the PRISMA guidelines and has been registered with PROSPERO (CRD420261378070) on 24 April 2026.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.