Evidence map›Paper›PMID 42755434›Full record

ArticleFrontiers in medicine2026

Diagnostic performance of ultrasonographic medial gastrocnemius muscle thickness for sarcopenia in patients on maintenance hemodialysis.

Meilin Yan, Wei An, Leting Zhou, Weiwei Shan, Xiran Zhang, Aiyan Du, Zhijian Zhang, Liang Wang

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meilin Yan *Department of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Wei An *Department of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Leting ZhouDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Weiwei ShanDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Xiran ZhangDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Aiyan DuDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Zhijian ZhangDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.
Liang WangDepartment of Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The study aimed to evaluate the performance of ultrasonographic medial gastrocnemius muscle thickness (MGMT) and pennation angle (MGMPA) in diagnosing sarcopenia among patients on maintenance hemodialysis (MHD). Methods: The MGMT and MGMPA were measured ultrasonographically. Baseline characteristics were compared between the sarcopenia and non-sarcopenia groups. Correlations between ultrasound parameters and sarcopenia indicators were evaluated. The diagnostic performance of the ultrasound parameters was assessed using receiver operating characteristic (ROC) curve analysis. Multivariable logistic regression analysis was conducted to identify independent predictors associated with sarcopenia, followed by the construction and validation of a diagnostic nomogram. Additionally, bootstrap mediation analysis assessed the direct and indirect effects of sonographic parameters on sarcopenia. Results: This study cohort comprised 221 MHD patients. Both MGMT (12.8 vs. 16.5 mm, Conclusion: Ultrasonographic measurement of MGMT demonstrates high diagnostic performance and serves as a reliable, independent predictor for sarcopenia in patients undergoing maintenance hemodialysis, highlighting its potential as a practical, non-invasive screening tool in clinical practice.

Indexed as

bioelectrical impedance analysishemodialysismedial gastrocnemius muscle thicknessmuscle ultrasoundsarcopenia

Identifiers

PMID42755434
PMCPMC13581512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.