Evidence map›Paper›PMID 42755161›Full record

ReviewGut microbes2026

Dietary and nutritional strategies for reducing disease risk associated with antibiotic-induced dysbiosis.

Hang Guo, Chengcheng Zhang, Ruimin Wang, Yijin Yang, Gang Wang, Shumao Cui, Wenwei Lu, Bo Yang, Xiaomei Lyu, Peijun Tian and 3 more

Abstract readReview
In one paragraph

Review in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hang GuoState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Chengcheng ZhangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Ruimin WangSchool of Food Science and Engineering, Hainan University, Haikou, People's Republic of China.
Yijin YangShanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, People's Republic of China.
Gang WangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0003-2007-2143
Shumao CuiState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-7055-0484
Wenwei LuState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-8636-9815
Bo YangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Xiaomei LyuState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Peijun TianState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-7833-1745
Fengwei TianState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-8511-4546
Jianxin ZhaoState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Qixiao ZhaiState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-0605-2675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic exposure is a major driver of gut microbiota dysbiosis, and its effects extend beyond transient diversity loss. Persistent alterations in microbial composition and metabolites disrupt intestinal barrier integrity, immune homeostasis, and host metabolic signaling, thereby increasing the risk of chronic diseases. Here, we review the evidence linking antibiotic-induced dysbiosis to disease susceptibility and argue that post-antibiotic recovery should target microbial functions and metabolic network restoration. We also examine a range of nutritional strategies, including dietary adjustments, prebiotics, probiotics, and bioactive nutrients, for their capacity to support beneficial commensal bacteria, restore key microbial metabolites, and enhance the gut ecosystem resilience. However, inter-individual variability in response complicates the development of universal protocols, and limited long-term clinical outcome data make it difficult to determine the clinical value of these interventions. Integrating nutritional science, microbial ecology, and precision medicine will be essential for developing effective personalized interventions.

Indexed as

Anti-Bacterial AgentsDietDysbiosisGastrointestinal MicrobiomeAnimalsBacteriaHumansPrebioticsProbioticsAnti-Bacterial AgentsPrebioticsAntibioticdietary patterndisease riskdysbiosisgut microbiotanutritional intervention

Identifiers

PMID42755161
PMCPMC13596897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.