Evidence map›Paper›PMID 42754894›Full record

ArticleJournal of nanobiotechnology2026

Simultaneous broad-spectrum antibacterial and regenerative therapy for diabetic wounds using sonosensitive peptide composite hydrogel.

Yao Lin, Baicheng Xing, Xiong Zhang, Guanghua Lu, Huaiyuan Zhang, Yuxin Zhang, Xingchao Wang, Ziyan Zhang, Zhong Wang, Ying Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yao Lin *State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Baicheng Xing *State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Xiong Zhang *State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Guanghua Lu *Department of Orthopedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Huaiyuan Zhang *Department of Orthopedics, Jinshan Hospital, Fudan University, Shanghai, 201508, China.
Yuxin ZhangState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Xingchao WangState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Ziyan ZhangState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Zhong WangDepartment of Neurology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, 210031, China.
Ying ZhangTongji Medical College, The Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, 430014, China.
Yong GaoState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Chunrui YangState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China.
Junyan ZhangDepartment of Emergency and Critical Disease, Shanghai Key Laboratory of Emotions and Affective Disorders, Songjiang Research Institute, Songjiang Hospital, Shanghai Jiao Tong University, Shanghai, 201600, China. junyanzhang@shsmu.edu.cn.
Wenyu QiaoDepartment of Orthopedics, Jinshan Hospital, Fudan University, Shanghai, 201508, China. qiaowenyu1226@163.com.
Yufeng ZhouState Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, 400016, China. yufeng.zhou@cqmu.edu.cn.

Funding

Chongqing Talent Program 2024030029the Fundamental Research Funds for the Central Universities YG2026QNB30the National Natural Science Foundation of China 12474450
6 · The paper itself

Abstract

Diabetic wound infections remain highly refractory to treatment due to persistent bacterial colonization, oxidative stress, dysregulated inflammation, vascular insufficiency, and impaired extracellular-matrix remodeling. Current therapeutic strategies remain limited by poor tissue penetration, inadequate infection control, and ineffective inflammatory-oxidative microenvironment modulation. Here, we engineered a sonosensitive antimicrobial peptide composite hydrogel, FFRK8@ZnO

Indexed as

Anti-Bacterial AgentsAntimicrobial PeptidesHydrogelsPeptidesAnimalsHumansHyaluronic AcidMiceOxidative StressUltrasonic WavesWound HealingAnti-Bacterial AgentsAntimicrobial PeptidesHyaluronic AcidHydrogelsPeptidesAngiogenesisAntibacterialDiabetic woundsImmune modulationLow intensity pulsed ultrasound (LIPUS)Multifunctional therapyPeptide composite hydrogel

Identifiers

PMID42754894
PMCPMC13587498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.