Evidence map›Paper›PMID 42754842›Full record

ArticleBMC emergency medicine2026

ECPR readiness without perfusionist support: a cross-sectional national survey on circuit preparation, team structure, and training.

Eva Mishuris, Alexander Wallraff, Rüdger Kopp, Jan Larmann, Lasse J Strudthoff, Christian Bleilevens, Patrick Winnersbach

Abstract read
In one paragraph

Article in BMC emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eva MishurisDepartment of Anaesthesiology, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Alexander WallraffDepartment of Heart Surgery, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.ORCID http://orcid.org/0009-0007-4779-1443
Rüdger KoppDepartment of Intensive Care, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Jan LarmannDepartment of Anaesthesiology, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0003-3365-4572
Lasse J StrudthoffBiorheology Research Laboratory, Griffith University, 1 Parklands Dr, Southport, Gold Coast, QLD, 4215, Australia.ORCID http://orcid.org/0000-0002-6810-6317
Christian BleilevensDepartment of Anaesthesiology, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0002-2104-1843
Patrick WinnersbachDepartment of Anaesthesiology, Medical Faculty, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany. pwinnersbach@ukaachen.de.ORCID http://orcid.org/0000-0001-6979-6818

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracorporeal cardiopulmonary resuscitation (ECPR) is a time-critical intervention for selected patients with refractory cardiac arrest. Survival depends on minimizing low-flow duration before ECPR initiation. Timely deployment requires organizational preparedness, trained personnel, and rapid extracorporeal membrane oxygenation (ECMO) circuit readiness. However, data on ECPR organization in centers operating without dedicated perfusionist support are limited.

methodsA nationwide cross-sectional online survey was conducted among German ECMO centers operating without perfusionist support. The questionnaire assessed circuit readiness, responsible personnel, training frequency, and the availability of standard operating procedures (SOPs).

resultsResponses from 42 centers were evaluated, of which 64% reported performing ECPR (n = 27). Most centers (90%, n = 38) had low annual ECMO volumes (< 50 cases). ECMO use was largely limited to the Cardiohelp and iLA activve/Xenios Console systems. Setup times were significantly shorter for ECPR than for non-ECPR ECMO: median 15 min (IQR 12-18; range 5-30) versus 30 min (IQR 20-40; range 15-105) (Mann-Whitney U = 46, p < 0.0001; Cliff's delta = 0.77; 95% CI 0.54-0.94). Nurses were more frequently involved in ECMO deployment in ECPR than in non-ECPR settings (59% (16/27 centers) vs. 20% (3/15 centers)). Within ECPR programs, regular training was reported more frequently for nurses than for physicians (87.5% (14/16 centers) vs. 60% (6/10 centers)). Overall, 76% (n = 32) of centers reported regular training (at least annually) for responsible personnel, 86% (n = 36) had internal SOPs in place, and 69% (n = 29) expressed the need for a universally applicable evidence-based SOP. All centers that reported a pre-defined maximum storage duration (n = 28) adhered to the Extracorporeal Life Support Organization guidelines regarding maximum storage duration of pre-assembled ECMO systems (30 days).

conclusionsGerman ECMO centers without perfusionist support reported substantial heterogeneity in ECPR readiness and operational workflows. ECPR-performing centers were associated with shorter setup times and more frequently reported interdisciplinary team structures and recurrent team training. These findings describe current organizational practices and perceived needs and support the value of interdisciplinary teamwork, structured training, and standardized protocols as organizational components that may facilitate timely, standardized ECPR deployment.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationHeart ArrestPatient Care TeamCross-Sectional StudiesGermanyHumansSurveys and QuestionnairesExtracorporeal cardiopulmonary resuscitation (ECPR)Extracorporeal membrane oxygenation (ECMO)Pre-assemblyPre-primingStandard operating procedures (SOPs)Team structureTraining

Identifiers

PMID42754842
PMCPMC13587460

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.