ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Multimodal non-pharmacological pain relief during adhesive tape removal in preterm infants: a randomized controlled trial.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06455631 (The Effect of Facilitated Tucking, Oral Breast Milk, and Kangaroo Care on Pain During Band Removal in Preterm Newborns), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Facilitated Tucking, Oral Breast Milk, and Kangaroo Care on Pain During Band Removal in Preterm Newborns
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of facilitated tucking combined with oral breast milk (FT + OBM) and kangaroo care combined with oral breast milk (KC + OBM) in reducing pain during adhesive tape removal in preterm infants. STUDY
designThis randomized controlled trial was conducted in a Level III NICU in Turkey and registered with the clinical trial ID NCT06455631. A total of 119 preterm infants (gestational age 30⁰⁄⁷-36⁶⁄⁷ weeks) were randomly assigned to FT + OBM, KC + OBM, or control groups. Pain was assessed using the Premature Infant Pain Profile-Revised, and physiological parameters were analyzed using generalized estimating equations.
resultsBoth intervention groups showed significantly lower pain scores than the control group (p < 0.001). Pain increased during tape removal but decreased afterward in both intervention groups. No significant difference was found between intervention groups.
conclusionTwo intervention groups are effective non-pharmacological strategies for reducing pain in preterm infants. CLINICAL
trial registrationThe trial has been registered on www. CLINICALTRIALS: gov , ID: NCT06455631. Patient enrollment began prior to trial registration due to the urgency of recruiting within a limited study period and delays in obtaining access to the trial registration platform. The study protocol was finalized and approved by the institutional ethics committee before enrollment, and no changes were made to the protocol after registration.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.