Evidence map›Paper›PMID 42753006›Full record

SynthesisNeurosurgical review2026

Cervical epidural venous engorgement after cerebrospinal fluid shunting: clinical-radiological correlation and systematic review.

Gianluca Scalia, Rosalba Pitoia, Roberta Finocchiaro, Lisa Passarello, Grazia Razza, Mariangela Panebianco, Stefano Chiriatti, Giuseppe Emmanuele Umana, Tiziana Cavallaro, Pietro Trombatore and 5 more

Abstract readSystematic ReviewCase Reports
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gianluca ScaliaNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy. gianluca.scalia@outlook.it.ORCID https://orcid.org/0000-0002-9465-2506
Rosalba PitoiaNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Roberta FinocchiaroNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Lisa PassarelloNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Grazia RazzaDepartment of Mental Health, ASP Catania, Catania, Italy.
Mariangela PanebiancoNeurology Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Stefano ChiriattiDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
Giuseppe Emmanuele UmanaDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
Tiziana CavallaroDepartment of Neuroradiology, Cannizzaro Hospital, Catania, Italy.
Pietro TrombatoreDepartment of Diagnostic Imaging, Interventional Radiology and Neuroradiology, Garibaldi Hospital, Catania, Italy.
Gianluca GalvanoDepartment of Diagnostic Imaging, Interventional Radiology and Neuroradiology, Garibaldi Hospital, Catania, Italy.
Giovanni NicolettiNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Salvatore CiceroDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.
Francesca GrazianoNeurosurgery Unit, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy.
Nicola AlberioDepartment of Neurosurgery, Trauma Center, Gamma Knife Center, Cannizzaro Hospital, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CSF shunting may cause overdrainage and intracranial hypotension. Cervical epidural venous engorgement is a rare but under-recognized complication that can result in spinal cord compression and myelopathy. We aimed to systematically characterize its clinical presentation, imaging features, management strategies, and outcomes, and to report an illustrative case. We conducted a PRISMA-guided systematic review of PubMed/MEDLINE, Scopus, and Web of Science from database inception to February 7, 2026. Forward and backward citation searching were additionally performed. Two reviewers independently screened studies, extracted data, and assessed methodological quality using the Joanna Briggs Institute (JBI) critical appraisal tools. Studies describing spinal epidural venous engorgement or related complications due to CSF shunting were included. Data were synthesized narratively. Fifteen studies comprising 16 previously reported patients were included in the qualitative synthesis. Median latency from shunt placement to symptom onset was 14.5 years (range 0.08-42). The predominant presentation was progressive cervical myelopathy, often without orthostatic headache. Imaging showed epidural venous plexus enlargement causing cervical spinal cord compression, typically at upper levels. Management focused on correcting overdrainage (valve adjustment, revision, or antisiphon devices) and resulted in clinical improvement in most cases. We report a 73-year-old patient with acute postoperative cervical epidural venous engorgement and hematoma after ventriculoperitoneal shunting for NPH, with complete resolution after valve reprogramming. Cervical epidural venous engorgement is a rare, reversible complication of CSF overdrainage that may present with myelopathy without typical intracranial hypotension symptoms. Early recognition and correction of CSF dynamics are essential to prevent neurological deterioration.

Indexed as

Cerebrospinal Fluid ShuntsPostoperative ComplicationsSpinal Cord CompressionAgedCervical VertebraeEpidural SpaceHumansIntracranial HypotensionCerebrospinal fluid shuntCervical myelopathyEpidural venous engorgementMiyazaki syndromeNormal pressure hydrocephalusShunt overdrainage

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.