Evidence map›Paper›PMID 42752898›Full record

ArticleSchmerz (Berlin, Germany)2026

[Analgesics and supportive care in the last month of life : Retrospective analysis of outpatient prescriptions using BARMER data from patients with oncological diseases (2016-2021)].

Ekaterina Slotina, Bianka Ditscheid, Franziska Meissner, Ursula Marschall, Winfried Meissner, Ulrich Wedding, Antje Freytag

Abstract readEnglish Abstract
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Article in Schmerz (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ekaterina SlotinaUniversitätsklinikum Jena, Institut für Allgemeinmedizin, Friedrich-Schiller-Universität Jena, Bachstrasse 18, 07743, Jena, Deutschland. slotina.ekaterina@gmail.com.
Bianka DitscheidUniversitätsklinikum Jena, Institut für Allgemeinmedizin, Friedrich-Schiller-Universität Jena, Bachstrasse 18, 07743, Jena, Deutschland.
Franziska MeissnerUniversitätsklinikum Jena, Institut für Allgemeinmedizin, Friedrich-Schiller-Universität Jena, Bachstrasse 18, 07743, Jena, Deutschland.
Ursula MarschallBARMER Institut für Gesundheitssystemforschung (bifg), Berlin, Deutschland.
Winfried MeissnerUniversitätsklinikum Jena, Abteilung für Palliativmedizin, Friedrich-Schiller-Universität Jena, Jena, Deutschland.
Ulrich WeddingUniversitätsklinikum Jena, Abteilung für Palliativmedizin, Friedrich-Schiller-Universität Jena, Jena, Deutschland.
Antje FreytagUniversitätsklinikum Jena, Institut für Allgemeinmedizin, Friedrich-Schiller-Universität Jena, Bachstrasse 18, 07743, Jena, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Germany, various forms of outpatient palliative care (PC) for oncological patients have been established for years. However, no data is available on how prescription rates of analgesics and supportive care vary depending on the specific form of outpatient PC.

methodsThis retrospective cohort study analyzed data from 158,035 deceased statutory health insurance patients with advanced cancer between 2016 and 2021. Three groups were analyzed: patients without outpatient PC, with general outpatient PC or particularly qualified and coordinated PC (AAPV/BQKPmV), and with specialized outpatient PC (SAPV). The study focused on the prescription rates of various medication groups according to ATC codes (nonopioid and opioid analgesics, antineuropathic medication, antiemetics, systemic steroids, stool-regulating measures) and their combinations in the last month of life.

resultsSAPV patients showed the highest prescription rates, e.g., strong opioids (71.8%), followed by AAPV/BQKPmV (47.2%) and patients without PC (22.5%). The prescription rates for all supportive medications showed similar patterns. An inverse pattern was observed for weak opioids: SAPV (5.8%), AAPV/BQKPmV (8.9%), and no PC (9.1%). The guideline-adherent combination of strong opioid analgesics and laxatives was implemented in less than half of the cases in SAPV (44.2%) and even less frequently in AAPV/BQKPmV (32.4%).

conclusionThis study provides comprehensive insights into medication prescription practices in outpatient PC in the last month of life, for the first time. The high prescription rates in SAPV reflects more intensive medication treatment of patients with possibly more complex symptoms in this specialized form of PC.

Indexed as

Administrative claims, healthcareDrug prescriptionHealth care utilizationOpioid analgesicPalliative supportive care

Identifiers

PMID42752898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.