Evidence map›Paper›PMID 42752812›Full record

ArticleFolia microbiologica2026

Weissella paramesenteroides M4: Optimization of bioprocesses, antioxidant property, and a potentially probiotic strain with in vitro activity against Cutibacterium acnes.

Heloísa Carneiro Colares, Tuânia Natacha Lopes Silva, Vinícius Souza Tarabal, Hiure Gomes Ramos Meira, Jéssica Ferreira Cardoso, Adriano Guimarães Parreira, José Antônio da Silva, Gisele Rodrigues da Silva, Juliana Teixeira de Magalhães, Daniel Bonoto Gonçalves and 1 more

Abstract read
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In one paragraph

Article in Folia microbiologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heloísa Carneiro ColaresBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0002-3354-5774
Tuânia Natacha Lopes SilvaBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0001-9399-1269
Vinícius Souza TarabalBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0002-8736-8531
Hiure Gomes Ramos MeiraBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0001-8563-3170
Jéssica Ferreira CardosoSchool of Pharmacy, Federal University of Ouro Preto, Professor Paulo Magalhães Gomes St., 122, Ouro Preto, MG, 35400-000, Brazil.ORCID http://orcid.org/0000-0001-7236-3853
Adriano Guimarães ParreiraDivinópolis Unit, State University of Minas Gerais. Paraná Av, Divinópolis, MG, 3001, 35501-170, Brazil.ORCID http://orcid.org/0000-0002-7770-7165
José Antônio da SilvaBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0001-9134-1211
Gisele Rodrigues da SilvaSchool of Pharmacy, Federal University of Ouro Preto, Professor Paulo Magalhães Gomes St., 122, Ouro Preto, MG, 35400-000, Brazil.ORCID http://orcid.org/0000-0001-5920-3521
Juliana Teixeira de MagalhãesMicrobiology Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil.ORCID http://orcid.org/0000-0002-0532-7323
Daniel Bonoto GonçalvesDepartment of Biosystems Engineering, Federal University of São, João del-Rei. Dom Helvécio Sq., 74, São João del-Rei, 36301-160, Brazil.ORCID http://orcid.org/0000-0002-8178-1026
Paulo Afonso GranjeiroBiotechnology Process and Macromolecules Purification Laboratory, Federal University of São, João del-Rei. Sebastião Gonçalves Filho St., 400, Divinópolis, MG, 35501-296, Brazil. granjeiro@ufsj.edu.br.ORCID http://orcid.org/0000-0003-0322-0861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin microbiota is linked to conditions such as acne. As antibiotic resistance limits the effectiveness of conventional treatments, microbiome-based strategies are needed. This study aimed to optimize the biomass production of Weissella paramesenteroides M4, evaluate its antioxidant properties, and assess its efficacy in a topical gel formulation against Cutibacterium acnes. Growth dynamics were established, followed by biomass optimization using fractional factorial and central composite rotatable designs with deproteinized whey as a sustainable substrate. Optimization increased biomass production by 974% (reaching 8.7 × 10

Indexed as

Acne vulgarisAnti-infective agentsBiotechnologyLactobacillalesMicrobiotaOptimizationPotential probiotics

Identifiers

PMID42752812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.