ArticlePLOS digital health2026
Utilization of a HIPAA-compliant large language model chatbot in an academic pediatric medical center.
Article in PLOS digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite growing interest in LLM chatbots, little evidence exists on usage patterns in hospital systems. This paper presents a mixed-methods case study of "InternalGPT," a HIPAA-compliant LLM chatbot made available to employees of the institution. Survey responses and 14 months of system utilization data were analyzed across diverse professional roles in the institution. Of approximately 15,800 hospital employees, 2,149 (13.6%) requested InternalGPT access. Motivations for sign-up aligned with professional roles: operations professionals prioritized administrative automation, clinicians focused on clinical augmentation, and scientists on research and coding. Among InternalGPT users, 52.8% recorded at least one token use; 33.6% never logged-in, and 13.7% logged-in but never used the tool. The top 20% of users consumed 69.4% of tokens. Key barriers to engagement among non-users included limited time for exploration (51.4%) and difficulty using (21.8%), integrating (15.5%), or accessing (9.2%) InternalGPT. Among a small group of employees with sustained InternalGPT use (n = 461), a subset who responded to a self-report survey (n = 92) indicated a mean productivity gain of 30%, corresponding to an exploratory perceived productivity value of $6.3M to $18.9M under varying extrapolation assumptions. Although most hospital employees never used the HIPAA-compliant LLM chatbot, a small minority who utilized it regularly reported substantial productivity improvements, highlighting both the value proposition of LLMs in healthcare and potential for increased engagement. Implementation and knowledge challenges were more frequently cited than AI-feature and performance concerns as key barriers to adoption. These findings underscore that successful LLM implementation in healthcare hinges not only on advanced AI technology, but also on robust system capacity building including investments in user education and technical integration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.