Evidence map›Paper›PMID 42752602›Full record

ArticlePLOS digital health2026

Utilization of a HIPAA-compliant large language model chatbot in an academic pediatric medical center.

Benjamin Rader, Dinesh K Rai, Melissa L Stewart, Sarah Lejfer, Sampath Chennuri, James Hartwell, Victor Moyano, Max H Witwer, Peter C Laussen, Heather L Nelson and 1 more

Abstract read
In one paragraph

Article in PLOS digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benjamin RaderInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-6095-0193
Dinesh K RaiInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Melissa L StewartInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Sarah LejferInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Sampath ChennuriInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
James HartwellInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Victor MoyanoInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Max H WitwerInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0009-0007-9520-9163
Peter C LaussenDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Heather L NelsonChief Information Officer, Boston Children's Hospital, Boston, Massachusetts, United States of America.
John S BrownsteinInnovation & Digital Health Accelerator, Boston Children's Hospital, Boston, Massachusetts, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite growing interest in LLM chatbots, little evidence exists on usage patterns in hospital systems. This paper presents a mixed-methods case study of "InternalGPT," a HIPAA-compliant LLM chatbot made available to employees of the institution. Survey responses and 14 months of system utilization data were analyzed across diverse professional roles in the institution. Of approximately 15,800 hospital employees, 2,149 (13.6%) requested InternalGPT access. Motivations for sign-up aligned with professional roles: operations professionals prioritized administrative automation, clinicians focused on clinical augmentation, and scientists on research and coding. Among InternalGPT users, 52.8% recorded at least one token use; 33.6% never logged-in, and 13.7% logged-in but never used the tool. The top 20% of users consumed 69.4% of tokens. Key barriers to engagement among non-users included limited time for exploration (51.4%) and difficulty using (21.8%), integrating (15.5%), or accessing (9.2%) InternalGPT. Among a small group of employees with sustained InternalGPT use (n = 461), a subset who responded to a self-report survey (n = 92) indicated a mean productivity gain of 30%, corresponding to an exploratory perceived productivity value of $6.3M to $18.9M under varying extrapolation assumptions. Although most hospital employees never used the HIPAA-compliant LLM chatbot, a small minority who utilized it regularly reported substantial productivity improvements, highlighting both the value proposition of LLMs in healthcare and potential for increased engagement. Implementation and knowledge challenges were more frequently cited than AI-feature and performance concerns as key barriers to adoption. These findings underscore that successful LLM implementation in healthcare hinges not only on advanced AI technology, but also on robust system capacity building including investments in user education and technical integration.

Identifiers

PMID42752602
PMCPMC13585266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.