Evidence map›Paper›PMID 42752236›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

FoldaVirus, a knowledge-based icosahedral capsid prediction tool using AlphaFold.

Oscar Rojas Labra, David S Montoya-Munoz, Nelly Santoyo-Rivera, Jeffrey McDonald, Daniel Montiel-Garcia, David A Case, Vijay S Reddy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oscar Rojas LabraThe Hormel Institute, University of Minnesota, Austin, MN 55912.ORCID 0000-0003-4920-1543
David S Montoya-MunozDepartment of Computer Systems and Information Technologies, Tecnologico Nacional de Mexico and Instituto Tecnológico Superior de Irapuato, Irapuato, Guanajuato C.P. 36821, Mexico.ORCID 0009-0002-7741-591X
Nelly Santoyo-RiveraDepartment of Computer Systems and Information Technologies, Tecnologico Nacional de Mexico and Instituto Tecnológico Superior de Irapuato, Irapuato, Guanajuato C.P. 36821, Mexico.ORCID 0009-0008-1894-9050
Jeffrey McDonaldThe Hormel Institute, University of Minnesota, Austin, MN 55912.ORCID 0000-0002-8538-3359
Daniel Montiel-GarciaDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.ORCID 0000-0002-5915-7016
David A CaseDepartment of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854.
Vijay S ReddyThe Hormel Institute, University of Minnesota, Austin, MN 55912.ORCID 0000-0003-4638-8277

Funding

Hormel Foundation (The Hormel Foundation) Startup Funds
6 · The paper itself

Abstract

Coat protein (CP) tertiary structures and their capsid organization of spherical viruses are generally well conserved within each virus family. While AlphaFold successfully predicts the tertiary structures of individual CPs, their association to form proper quaternary assemblies cannot be easily accomplished. Here, we report a generalized methodology and an associated web-based utility (https://foldavirus.org) that combines AlphaFold predictions of CPs with the knowledge on corresponding icosahedral architectures (e.g.,

Indexed as

CapsidCapsid ProteinsSoftwareModels, MolecularCapsid ProteinsAlphaFoldcapsid modelsT-numberviral capsidsvirus structures

Identifiers

PMID42752236
PMCPMC13598199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.