Evidence map›Paper›PMID 42752200›Full record

ArticleMicrobiology spectrum2026

Population heterogeneity in

Dowon Seo, Jaeyun Nam, Minseo Kim, Sungkyeong Lee, Jiwon Seo, Sacheera Angulmaduwa, Ashansa Ramanayake, Roshan Pradeep, Jing Lai, Eun-Jung Bak and 5 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dowon Seo *Department of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0009-0002-6468-634X
Jaeyun Nam *Department of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0009-0002-4837-5859
Minseo KimDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Sungkyeong LeeDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Jiwon SeoDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Sacheera AngulmaduwaDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Ashansa RamanayakeDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Roshan PradeepDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Jing LaiDepartment of Periodontics, Changsha Stomatological Hospital, Changsha, Hunan, China.
Eun-Jung BakDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Yong-Joon ChoDepartment of Molecular Bioscience, Kangwon National University, Chuncheon, Republic of Korea.
Eui-Jeong NohDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Sungil JangDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0000-0001-6144-6899
Myeong-A KimDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0000-0002-1540-4425
Jeong-Heon ChaDepartment of Oral Biology, Oral Science Research Center, BK21 Four Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0000-0002-9385-2653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental infection models are widely used to investigate host-microbe interactions, often under the assumption that bacterial populations are genetically uniform. Here, we examined population heterogeneity in the widely used IMPORTANCE: Animal infection models are widely used to study how bacterial pathogens cause disease and change during infection. These studies often assume that the bacteria used for infection are genetically uniform. Our study shows that this assumption may not always hold. We found that a commonly used

Indexed as

Helicobacter InfectionsHelicobacter pyloriAnimalsDisease Models, AnimalFemaleGenetic HeterogeneityGenetic VariationGenome, BacterialMiceHelicobacter pylorihost-pathogen interactionmouse infectivityPMSS1PMSS2population heterogeneitywhole-genome sequencing

Identifiers

PMID42752200
PMCPMC13689314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.