Evidence map›Paper›PMID 42751900›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

[Combined detection of urinary-related protein and fecal calprotectin for early warning of IgA vasculitis with nephritis in children].

Lin-Yan Ye, Ren-Bin Zhou, Min Xie, Hai-Rong Zhou, Xin-Zhou Chen

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Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Lin-Yan YeDepartment of Pediatrics, Yichun People's Hospital, Yichun, Jiangxi 336000, China.
Ren-Bin ZhouDepartment of Pediatrics, Yichun People's Hospital, Yichun, Jiangxi 336000, China.
Min XieDepartment of Pediatrics, Yichun People's Hospital, Yichun, Jiangxi 336000, China.
Hai-Rong ZhouDepartment of Pediatrics, Yichun People's Hospital, Yichun, Jiangxi 336000, China.
Xin-Zhou ChenDepartment of Pediatrics, Yichun People's Hospital, Yichun, Jiangxi 336000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the early warning value of combined detection of urinary neutrophil gelatinase-associated lipocalin (NGAL), urinary microalbumin and fecal calprotectin for IgA vasculitis with nephritis (IgAVN).

methodsA total of 90 children with IgAV and 50 healthy children undergoing physical examination at Yichun People's Hospital from January 2024 to December 2025 were enrolled. Based on urinalysis at admission and at 3-month follow-up, IgAV cases were classified into a simple IgAV group (

resultsLevels of urinary NGAL, urinary microalbumin and fecal calprotectin in the IgAVN group were significantly higher than those in the simple IgAV group and the control group (

conclusionsCombined detection of urinary NGAL, urinary microalbumin and fecal calprotectin improves early warning for IgAVN in children, providing a reliable laboratory basis for early clinical intervention and better prognosis.

Indexed as

FecesIgA VasculitisImmunoglobulin ALeukocyte L1 Antigen ComplexLipocalin-2NephritisVasculitisAdolescentAlbuminuriaBiomarkersChildChild, PreschoolFemaleHumansMaleROC CurveBiomarkersImmunoglobulin ALCN2 protein, humanLeukocyte L1 Antigen ComplexLipocalin-2ChildFecal calprotectinIgA vasculitis with nephritisNeutrophil gelatinase-associated lipocalinUrinary microalbuminWarning

Identifiers

PMID42751900
PMCPMC13584575

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