ArticlePlastic and reconstructive surgery. Global open2026
Final 2-year Results From the ROBUST Trial of Office-based Ultrasound-guided Carpal Tunnel Release.
Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
8 authors.
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Abstract
Background: There has been a growing interest in transitioning carpal tunnel release procedures to the office setting. We report the final 2-year safety and effectiveness outcomes of office-based ultrasound-guided carpal tunnel release (UGCTR). Methods: ROBUST was a prospective multicenter observational study of adults with idiopathic carpal tunnel syndrome who underwent office-based UGCTR. Main outcomes included time to return to normal activities and work, Boston Carpal Tunnel Questionnaire Symptom Severity Scale and Functional Status Scale, Michigan Hand Questionnaire, pain severity (0-10 scale), health-related quality of life measured using the EuroQoL 5-Dimension 5-Level index, overall patient satisfaction, and complications. A subgroup analysis compared outcomes of unilateral and simultaneous bilateral procedures. Results: The trial enrolled 149 patients across 7 sites who underwent office-based UGCTR under wide-awake local anesthesia no-tourniquet (72 unilateral; 77 simultaneous bilateral). Median time to return to normal activities and work was 2 and 4 days, respectively. Follow-up compliance was 92.6% at 2 years. All patient-reported outcomes improved significantly from baseline ( Conclusions: Office-based UGCTR safely provided durable symptom relief, functional improvement, and high patient satisfaction during the 2-year follow-up, with comparable outcomes between unilateral and simultaneous bilateral procedures.
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