Evidence map›Paper›PMID 42751671›Full record

ArticleEndoscopic ultrasound

Optimal timing for hepatic cyst intervention: Predictive factors for complete resolution after ethanol sclerotherapy.

Yoonchan Lee, Dong-Wan Seo, Sung Hyun Cho, Gunn Huh, Dongwook Oh, Tae Jun Song

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In one paragraph

Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yoonchan LeeDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Dong-Wan SeoDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Sung Hyun ChoDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Gunn HuhDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Dongwook OhDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Tae Jun SongDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: The optimal timing of ethanol sclerotherapy and predictors of complete resolution (CR) in patients with symptomatic hepatic cysts remain unclear. This study aimed to identify clinical and procedural predictors of CR and to determine a volume-based threshold that may guide patient selection. Methods: We retrospectively analyzed 307 patients who underwent percutaneous catheter drainage-guided or EUS-guided ethanol sclerotherapy between 2003 and 2023. CR was defined as <5% of baseline cyst volume. Receiver operating characteristic analysis identified a volume threshold for CR, and multivariable logistic regression was used to determine independent predictors. Results: CR was achieved in 54.4% of patients during a mean follow-up of 24.7 ± 21.1 months. An initial cyst volume of 233 mL (≈7-8 cm in diameter) was identified by receiver operating characteristic analysis as a threshold associated with CR (area under the curve 0.626; sensitivity 50.9%; specificity 75.0%). CR rates were significantly higher in cysts <233 mL than in larger cysts (70.6% Conclusion: Initial hepatic cyst volume is an important factor influencing treatment outcome. The 233 mL threshold may inform the timing of intervention alongside symptoms and patient-specific factors.

Indexed as

endosonographyliver cystssclerotherapy

Identifiers

PMID42751671
PMCPMC13581355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.