ArticleCureus2026
Extreme Carcinoembryonic Antigen Elevation Revealing Clinically Silent Colonic Metastases From Gastric Adenocarcinoma: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Gastric adenocarcinoma rarely metastasizes to the colon, and extreme carcinoembryonic antigen (CEA) elevation exceeding 1,000 ng/mL occurs in approximately 1.3% of gastric cancers, where it is strongly associated with lymphatic dissemination and poorly differentiated histology. We report the case of a 47-year-old man with progressive constitutional symptoms in whom markedly elevated CEA prompted a comprehensive diagnostic workup, ultimately revealing stage IV gastric adenocarcinoma with clinically silent colonic metastases. Computed tomography demonstrated numerous pulmonary nodules, mediastinal and hilar lymphadenopathy, and a 3.5-cm periceliac mass with diffuse retroperitoneal and retrocrural adenopathy, without hepatic lesions or peritoneal implants. Initial CEA exceeded 600 ng/mL and subsequently rose to 1,170 ng/mL. Notably, endoscopy performed four years earlier had revealed only mild chronic erosive gastritis without
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