ArticlePediatric health, medicine and therapeutics2026
Cytomegalovirus-Associated Thrombocytopenia in an Immunocompetent Infant: A Case Report.
Article in Pediatric health, medicine and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cytomegalovirus (CMV) is a β-herpesvirus. In immunocompromised individuals, CMV infection can cause life-threatening complications such as encephalitis, pneumonia, hepatitis and organ rejection. In contrast, immunocompetent children often present with mild infection, with thrombocytopenia being a common hematological complication. Methods: A 2-month-18-day-old female infant was transferred to a tertiary hospital due to a 2-day fever and 1-day generalized petechiae. Physical examination revealed scattered skin petechiae without lymphadenopathy, hepatosplenomegaly or other systemic symptoms. Laboratory tests showed moderate thrombocytopenia with a platelet count of 35 × 10 Results: The platelet count and liver function improved gradually during hospitalization. At two-week follow-up after discharge, blood cell parameters and liver enzymes returned to normal, and peripheral CMV-DNA declined to undetectable levels. Platelet counts remained stable in the subsequent 2-month follow-up. Conclusion: CMV-associated thrombocytopenia in immunocompetent infants is usually self-limiting. Close dynamic monitoring of hematological and hepatic indicators is essential. Antiviral therapy should be prescribed cautiously, and individualized management is recommended for mild CMV infection in young infants.
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