Evidence map›Paper›PMID 42751589›Full record

ArticleJournal of medicine and life2026

Timing of alveolar bone surgery as a predictor of guided bone regeneration success: results of a retrospective cohort study.

Radu Ioan Neacșu, Alexandru Metea, Horia Nițu, Bogdan Toropu, Mihai Soare, Amelia Bucur, Alina Ormenișan

Abstract read
In one paragraph

Article in Journal of medicine and life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Radu Ioan NeacșuFaculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, Târgu Mureș, Romania.
Alexandru MeteaDepartment of Oral and Maxillofacial Surgery, Dr. Alexandru Augustin Emergency Military Clinical Hospital, Sibiu, Romania.
Horia NițuDepartment of Oral and Maxillofacial Surgery, Dr. Alexandru Augustin Emergency Military Clinical Hospital, Sibiu, Romania.
Bogdan ToropuDepartment of Oral and Maxillofacial Surgery, Dr. Alexandru Augustin Emergency Military Clinical Hospital, Sibiu, Romania.
Mihai SoareDepartment of Oral and Maxillofacial Surgery, County Emergency Clinical Hospital, Sibiu, Romania.
Amelia BucurDepartment of Mathematics and Informatics, Faculty of Sciences, Lucian Blaga University, Sibiu, Romania.
Alina OrmenișanDepartment of Oral and Maxillofacial Surgery, Dr. Alexandru Augustin Emergency Military Clinical Hospital, Sibiu, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiological condition of bone prior to regenerative procedures has received little attention, with concerns more often related to technical and biomaterial issues. The primary aim of the study was to test whether pathophysiological changes in bone following tooth extractions or other alveolar bone surgery have an additional impact on bone growth in guided bone regeneration (GBR) with collagen membranes. A total of 33 consecutive patients with vertical and horizontal atrophy of the alveolar ridges, comprising 70 dental sites, treated with staged GBR using collagen membranes and a resorbable graft material, were analyzed in terms of the specific results of the procedure. The effect of defect morphology and recent bone surgery on the critical dimensions of the alveolar ridge was assessed by superimposing serial cone-beam computed tomography (CBCT) images before the augmentation procedure and after the bone healing period. Complex defects and recent bone surgeries, not older than 6 months, showed the greatest increase in crest width: 6.42 mm (

Indexed as

Alveolar ProcessAlveolar Ridge AugmentationBone RegenerationGuided Tissue RegenerationGuided Tissue Regeneration, PeriodontalAdultCollagenCone-Beam Computed TomographyFemaleHumansMaleMiddle AgedRetrospective StudiesCollagenAB, autogenous boneABT, antibiotic therapyalveolar ridge atrophyANOVA, analysis of varianceBSP, bone sialoproteinBW, base widthCBCT, cone-beam computed tomographycollagen membranecomplicationsCW, crest widthDBB, deproteinized bovine bonedental extractionsGBR, guided bone regenerationguided bone regenerationH, heightM-CSF, macrophage colony-stimulating factorOCN, osteocalcinOPG, osteoprotegerinOPN, osteopontinOR, odds ratiopredictive factorRANK, receptor activator of nuclear factor κBRAP, regional acceleratory phenomenonregional acceleratory phenomenonresorbable graft biomaterialsSAP, systemic acceleratory phenomenonSD, standard deviationTNF, tumor necrosis factor

Identifiers

PMID42751589
PMCPMC13580514

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.