ArticleCureus2026
Effect of Low-Level Laser Therapy on Implant Osseointegration and Peri-Implant Clinical Outcomes: A Prospective Observational Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
introductionLow-level laser therapy (LLLT) has been proposed as an adjunctive modality to enhance osseointegration and improve peri-implant healing after dental implant placement. However, evidence regarding its clinical effectiveness remains inconclusive. This study evaluated the effects of adjunctive LLLT on implant stability, marginal bone remodeling, peri-implant probing depth, and postoperative complications over a 12-month follow-up period. MATERIALS AND
methodsA prospective observational clinical study was conducted on 80 dental implants placed in patients requiring single-tooth implant rehabilitation. Following standardized implant placement, all participants received LLLT using an Epic X diode laser (BIOLASE, Inc., Foothill Ranch, CA, USA) immediately after surgery and on postoperative days 3, 7, and 14. Implant stability was assessed using resonance frequency analysis, whereas radiographic marginal bone levels and peri-implant probing depth were evaluated at prosthetic loading, at six months, and at 12 months. Data were analyzed using repeated-measures analysis of variance with Bonferroni-adjusted post hoc testing.
resultsImplant stability improved significantly during follow-up, with the mean implant stability quotient increasing from 67.98 ± 4.02 at implant placement to 74.28 ± 4.54 at 12 months (p < 0.001). Marginal bone loss increased gradually from 0.19 ± 0.08 mm at prosthetic loading to 0.55 ± 0.16 mm at 12 months but remained within clinically acceptable limits (p < 0.001). Mean peri-implant probing depth increased modestly from 2.13 ± 0.47 mm to 2.52 ± 0.61 mm during follow-up (p < 0.001). No complications were observed in 71 (88.8%), 69 (86.2%), and 64 (80.0%) implants at prosthetic loading, six months, and 12 months, respectively.
conclusionAdjunctive LLLT was accompanied by progressive improvement in implant stability, favorable peri-implant tissue healing, acceptable marginal bone remodeling, and a low incidence of postoperative complications during the 12-month follow-up period. However, in the absence of a control group, these outcomes cannot be attributed specifically to LLLT. Larger randomized controlled trials with longer follow-up periods are required to determine whether LLLT provides additional clinical benefits beyond conventional implant healing.
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