Evidence map›Paper›PMID 42751563›Full record

Trial reportFrontiers in nutrition2026

Polyphenol-rich sugarcane extract reduces circulating

Simone Lewin, Claudia Hartley, Thalia Marina Llalla Vidal, Jayson J A Rose, Andrew Costanzo, Snehal R Jadhav, Jacoba Bromfield, Russell S J Keast, Shane Mitchell, Matthew Flavel and 1 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simone LewinARC Training Centre for Hyphenated Analytical Separation Technologies (HyTECH), Hobart, TAS, Australia.
Claudia HartleyDeakin Centre for Advanced Food Sciences, School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
Thalia Marina Llalla VidalBioactives Division, The Product Makers Australia Pty Ltd., Keysborough, VIC, Australia.
Jayson J A RoseDepartment of Microbiology, Anatomy, Physiology and Pharmacology, La Trobe University, Bundoora, VIC, Australia.
Andrew CostanzoDeakin Centre for Advanced Food Sciences, School of Exercise and Nutrition Sciences, Deakin University, Burwood, VIC, Australia.
Snehal R JadhavARC Training Centre for Hyphenated Analytical Separation Technologies (HyTECH), Hobart, TAS, Australia.
Jacoba BromfieldCmbio, Fruebjergvej, Copenhagen, Denmark.
Russell S J KeastARC Training Centre for Hyphenated Analytical Separation Technologies (HyTECH), Hobart, TAS, Australia.
Shane MitchellBioactives Division, The Product Makers Australia Pty Ltd., Keysborough, VIC, Australia.
Matthew FlavelARC Training Centre for Hyphenated Analytical Separation Technologies (HyTECH), Hobart, TAS, Australia.
Daniel Anthony DiasARC Training Centre for Hyphenated Analytical Separation Technologies (HyTECH), Hobart, TAS, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polyphenol-rich sugarcane extracts (PRSEs) are food-derived sources of naturally occurring bioactive polyphenols with increasing relevance to metabolic regulation, gut microbiome function, and overall well-being. Objective: This fully remote trial investigated the effects of PRSE supplementation on cardiometabolic biomarkers and gut microbiota. Methods: Healthy adults aged 18-55 years ( Results: Significant treatment × time effects were observed for circulating Conclusion: PRSE supplementation was associated with a lower circulating proportion of Clinical trial registration: https://anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386733&isReview=true, identifier, ANZCTR; ACTRN12624000055505.

Indexed as

gut microbiomepolyphenol-rich sugarcane extractpolyphenolsrandomised controlled trialtrans-fatty acidstriglyceridesVLDL

Identifiers

PMID42751563
PMCPMC13580332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.