Evidence map›Paper›PMID 42751552›Full record

ArticleBioactive materials2027

Acoustoelectric nanoregulator for modulating the endoplasmic reticulum and mitochondria in cell fate regulation.

Guoqing Feng, Guoxin Han, Yang Bai, Bowen Li, Feiyu Zhao, Run Yang, Xuheng Chen, Renwang Liu, Niansong Qian, Bin Zheng and 1 more

Abstract read
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In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guoqing FengState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Guoxin HanDepartment of Emergency, The Ninth Medical Center of PLA General Hospital, Beijing, 100101, China.
Yang BaiState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Bowen LiState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Feiyu ZhaoDepartment of Radiation Therapy, Oncology Medical Department, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Run YangState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Xuheng ChenState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Renwang LiuDepartment of Lung Cancer Surgery, Center of Thoracic Surgery, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Niansong QianDepartment of Respiratory, The Eighth Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Bin ZhengState Key Laboratory of Synthetic Biology, Medical School of Tianjin University, Tianjin University, Tianjin, 300072, China.
Shanlong ZhangDepartment of Clinical Laboratory, The Second Affiliated Hospital of Shandong First Medical University, Taian, 271000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) and mitochondria are critical organelles in maintaining cellular homeostasis and regulating cell fate. However, current biological and chemical approaches for modulating ER and mitochondrial functions often lack specificity and spatiotemporal controllability, potentially leading to off-target or systemic effects that limit their clinical applications. Here, by synthesizing a physical stimulus-based acoustoelectric nanoregulator, barium zirconate titanate (BZT) nanoparticles (NPs) with enhanced piezoelectric properties, we aimed to modulate ER and mitochondrial functions by regulating intracellular concentrations of calcium ions (Ca

Indexed as

Acoustoelectric nanoregulatorEndoplasmic reticulum stressMitophagyPiezoelectric nanomaterials

Identifiers

PMID42751552
PMCPMC13580056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.