ReviewFrontiers in bioengineering and biotechnology2026
A breath of fresh air: the role of oxygen carriers in plastic surgery.
Review in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Tissue hypoxia represents a major challenge in regenerative medicine because it may impair wound healing and contribute to tissue necrosis and eventually reconstructive failure. To overcome this problem, topically applied oxygen carriers have emerged as a promising strategy to enhance tissue oxygenation independently of vascular function. This narrative review summarizes the clinical evidence for the use of oxygen carriers in plastic, reconstructive and aesthetic surgery. Four principal categories were identified, including hemoglobin-, peroxide-, and microalgae-based oxygen carriers as well as physical oxygen carriers. Hemoglobin- and peroxide-based oxygen carriers have shown beneficial effects on wound healing. However, evidence from randomized controlled trials remains inconsistent and large-scale studies for other indications are limited. In an early clinical study, microalgae-seeded scaffolds enabled controlled
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