Evidence map›Paper›PMID 42751476›Full record

ArticleThe journal of liquid biopsy2026

Circulating immune profiling reveals immune signatures associated with disease stage and outcome in endometrial cancer.

Raquel Piñeiro-Pérez, Ana Vilar, Efigenia Arias, Victoria Sampayo, Alicia Abalo-Piñeiro, Carmela Rodríguez, Alexandra Cortegoso, Raúl Márquez, Eva Díaz, Gema Moreno-Bueno and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of liquid biopsy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Raquel Piñeiro-PérezTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Ana VilarGynecology Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, Spain.
Efigenia AriasGynecology Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, Spain.
Victoria SampayoGynecology Department, University Clinical Hospital of Santiago de Compostela (SERGAS), Santiago de Compostela, Spain.
Alicia Abalo-PiñeiroTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Carmela RodríguezTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Alexandra CortegosoTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Raúl MárquezMedical Oncology Department, MD Anderson Cancer Center, C/Arturo Soria 270, Madrid, 28033, Spain.
Eva DíazFundación MD Anderson Internacional, Madrid, Spain.
Gema Moreno-BuenoFundación MD Anderson Internacional, Madrid, Spain.
Isabel PalacioHospital Universitario Central de Asturias, Department of Medical Oncology, Oviedo, Spain.
Sonia Blanco-PrietoInstituto de Investigación Sanitaria Galicia Sur, Vigo, Spain.
Lidia Vázquez-TuñasInstituto de Investigación Sanitaria Galicia Sur, Vigo, Spain.
Isaura Fernández-PérezInstituto de Investigación Sanitaria Galicia Sur, Vigo, Spain.
Ester Munera-MaravillaCentro de Investigación Biomédica en Red de Cáncer (CIBERONC), Monforte de Lemos 3, 5, Madrid, 28029, Spain.
Silvia CalabuigCentro de Investigación Biomédica en Red de Cáncer (CIBERONC), Monforte de Lemos 3, 5, Madrid, 28029, Spain.
Cristina CaballeroServicio de Oncología Médica, Hospital General Universitario de Valencia, Valencia, Spain.
Ana HerreroHospital Universitario Miguel Servet, Zaragoza, Spain.
Rafael López-LópezTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Juan CuevaTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.
Juan E Viñuela-RoldánInmunología, Servicio de Análisis Clínicos, Complexo Hospitalario Universitario de Santiago de Compostela, SERGAS, A Coruña, Spain.
Laura Muinelo-RomayTranslational Medical Oncology (Oncomet)/ Liquid Biopsy Analysis Unit, Health Research Institute of Santiago (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, 15706, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the tumor immune microenvironment has been studied in endometrial cancer, the systemic immune alterations associated with disease progression and their potential prognostic significance remain poorly defined. In this study, peripheral blood immune subsets were characterized by multiparametric flow cytometry in 67 patients with EC and 20 healthy controls, including dendritic cells, MDSCs, T-cell subsets, NK cells, and exhaustion and senescence associated markers. Immune profiles were similar between healthy controls and patients with early-stage disease, whereas advanced tumors showed marked changes, including dendritic cell expansion, reduced CD4

Indexed as

Candidate biomarkersEndometrial cancerFlow cytometryLiquid biopsyTumor immunology

Identifiers

PMID42751476
PMCPMC13579920

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.